ND GB300-v6 sizes series

The NDGB300v6 series is Azure’s next-generation GPU VM line purpose-built for large-scale AI, especially high-throughput inference for reasoning and agentic systems. These VMs are powered by NVIDIA GB300 NVL72 rackscale systems (Blackwell Ultra GPUs + Grace CPUs).  Each ND-GB300-v6 VM has two NVIDIA Grace CPUs and four NVIDIA Blackwell B300 GPUs. The GPUs are interconnected via fifth-generation NVLINK, providing a total of 4× 1.8 TB/s NVLINK bandwidth per VM. Each GPU also has 800 Gb/s InfiniBand connectivity, enabling cluster-scale performance with low latency. There are 18 VMs per rack, so effectively 72 NVIDIA Blackwell Ultra GPUs with 36 NVIDIA Grace CPUs, exposing ~37 TB of fast memory (~20TB High Bandwidth Memory, ~17TB of CPU Memory), 130 TB/s of intrarack NVLink bandwidth.

At rack scale, ND GB300 v6 delivers up to 1.44 exaFLOPS FP4 Tensor Core performance per NVL72 domain and has demonstrated ~1.1 million tokens/second LLM inference throughput per rack, which is ~27% higher than ND GB200 v6. See here for more details. Compared to GB200, GB300 provides ~1.5× FP4 compute, 50% higher HBM capacity (288 GB HBM3E per GPU vs. 192 GB), and 2x the back-end network bandwidth per GPU (800Gbps vs 400 Gbps).

The ND GB300 v6 architecture builds on the ND v6 GB200 to efficiently distribute workloads and memory demands across multiple GPUs, driving markedly higher inference throughput for long context and multimodal workloads AI and scientific applications. These instances deliver best-in-class performance for AI, ML, and analytics workloads with out-of-the-box support for frameworks like PyTorch, Tensorflow, JAX, RAPIDS, and more.

Host specifications

Part	Quantity ^{Count Units}	Specs ^{SKU ID, Performance Units, etc.}
Processor	128 vCPUs	Nvidia Grace CPU
Memory	864 VM	LPDDR
Local Storage	4 Disks	16TB NVME Direct
Remote Storage	16 Disks	80000 IOPS/1200 MBps
Network	1 NICs	160Gb/s Ethernet
Accelerators	4 GPUs	Nvidia Blackwell Ultra GPU (288GB)

For features supported by this series, see the Feature support section.

Sizes in series

vCPUs (Qty.) and Memory for each size

Size Name	vCPUs (Qty.)	Memory (GB)
Standard_ND128isr_GB300_v6	128	864

VM Basics resources

Check vCPU quotas

Local (temp) storage info for each size

Size Name	Max Temp Storage Disks (Qty.)	Temp Disk Size (TB)
Standard_ND128isr_GB300_v6	4	16

Storage resources

Table definitions

Temp disk speed often differs between RR (Random Read) and RW (Random Write) operations. RR operations are typically faster than RW operations. The RW speed is usually slower than the RR speed on series where only the RR speed value is listed.
Storage capacity is shown in units of GiB or 1024^3 bytes. When you compare disks measured in GB (1000^3 bytes) to disks measured in GiB (1024^3) remember that capacity numbers given in GiB may appear smaller. For example, 1023 GiB = 1098.4 GB.
Disk throughput is measured in input/output operations per second (IOPS) and MBps where MBps = 10^6 bytes/sec.
To learn how to get the best storage performance for your VMs, see Virtual machine and disk performance.

Remote (uncached) storage info for each size

Size Name	Max Remote Storage Disks (Qty.)	Uncached Disk IOPS	Uncached Disk Speed (MBps)
Standard_ND128isr_GB300_v6	16	80000	1200

Storage resources

Table definitions

Some sizes support bursting to temporarily increase disk performance. Burst speeds can be maintained for up to 30 minutes at a time.
Special Storage refers to either Ultra Disk or Premium SSD v2 storage.
Storage capacity is shown in units of GiB or 1024^3 bytes. When you compare disks measured in GB (1000^3 bytes) to disks measured in GiB (1024^3) remember that capacity numbers given in GiB may appear smaller. For example, 1023 GiB = 1098.4 GB.
Disk throughput is measured in input/output operations per second (IOPS) and MBps where MBps = 10^6 bytes/sec.
Data disks can operate in cached or uncached modes. For cached data disk operation, the host cache mode is set to ReadOnly or ReadWrite. For uncached data disk operation, the host cache mode is set to None.
To learn how to get the best storage performance for your VMs, see Virtual machine and disk performance.

Network interface info for each size

Size Name	Max Front-end NICs (Qty.)	Max Front-end Bandwidth (Mbps)	Max Scale-up NICS (Qty.)	Max Scale-Up Bandwidth (TBps)¹	Max Scale-out NICS (Qty.)	Max Scale-Out Bandwidth (Gbps)²
Standard_ND128isr_GB300_v6	1	160	4	1.8	4	4x800

Networking resources

Table definitions

¹ Bandwidth is per NIC to up to 100,000 of GPUs through InfiniBand
² Bandwidth is up to 72 GPUs per domain through NVLINK
Expected network bandwidth is the maximum aggregated bandwidth allocated per VM type across all NICs, for all destinations. For more information, see Virtual machine network bandwidth
Upper limits aren't guaranteed. Limits offer guidance for selecting the right VM type for the intended application. Actual network performance will depend on several factors including network congestion, application loads, and network settings. For information on optimizing network throughput, see Optimize network throughput for Azure virtual machines.
To achieve the expected network performance on Linux or Windows, you may need to select a specific version or optimize your VM. For more information, see Bandwidth/Throughput testing (NTTTCP).

Size Name	Accelerators (Qty.)	Accelerator-Memory (GB)
Standard_ND128isr_GB300_v6	4	288

Feature support

Feature name	Support status
Premium Storage	Supported
Premium Storage caching	Supported
Live Migration	Not Supported
Memory Preserving Updates	Not Supported
Generation 2 VMs	Supported
Generation 1 VMs	Not Supported
Accelerated Networking	Supported
Ephemeral OS Disk	Supported
Nested Virtualization	Not Supported

Other size information

List of all available sizes: Sizes

Pricing Calculator: Pricing Calculator

Information on Disk Types: Disk Types

Next steps

Take advantage of the latest performance and features available for your workloads by changing the size of a virtual machine.

Utilize Microsoft's in-house designed ARM processors with Azure Cobalt VMs.

Learn how to Monitor Azure virtual machines.

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Last updated on 2026-03-10

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ND GB300-v6 sizes series

Host specifications

Sizes in series

VM Basics resources

Feature support

Other size information

Next steps

Feedback

Additional resources